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Conference Information

Welcome Message!

In continuation with the past Alzheimers 2021 Pulsus group proudly invites all the participants and sponsors across the world to participate within the 13^th International conference on Dementia and Alzheimer Diseases (Alzheimers2021) which can be held during November 15, 2021, as a Webinar.

The main aim of our conference is to bring the renowned neurologist, neurosurgeons, researchers, health care professionals and special educators under one place to share their knowledge and scientific progress within the field of dementia and Alzheimer diseases within the theme Delving into the Advancements of Dementia and Alzheimer's care

Our conference includes a well-balanced line from speakers, covering both broad specific topics of interest. Our aim is to gather the neurosurgeon, specialists and anyone professionally involved in dementia diseases with a chance to find out about the complex nature of the diseases, understand the local realities and find out better remedy for the dementia conferences, we hope that you simply will grab the chance and accompany us.

This year’s conference is not any exception and brings together Alzheimer’s, dementia, neurology, psychiatry researchers, professors, students, delegates from across the world to debate the latest improvements during this intervention and continuously developing field of Alzheimers and Dementia.

We hope that the event will challenge and encourage you, and leads to unveiling knowledge, friendships, and collaborations, despite the stimulating program you'll be ready to enjoy the entire session during this lockdown of pandemic outbreak.

Looking forward to catching up with this excellent Event!!

Scientific Sessions

Track 1: Alzheimers Diseases

Alzheimer's sickness is that the start of mild reminiscence loss, that's thanks to a scarcity of ability to perform important tasks. Alzheimer's sickness is an irreversible, progressive brain disorder that often impairs memory and thinking abilities, also because the cap potential to hold out even the utmost simple tasks. Alzheimer's disease may be a circumstance during which the signs and symptoms of dementia regularly boom over time. Reminiscence loss is slight withinside the first stages of Alzheimer's, however with late-level Alzheimer's, one loses the power to require part in sports activities and reply to others. Alzheimer's sickness has no treatment, however there are therapeutic drugs for the signs and symptoms, and studies continues.

Track 2: Dementia

Dementia may be a syndrome during which deterioration within the memory, thinking and causes other problems within the brain. Dementia mainly affects the older people instead of younger people. In per annum, 10 million peoples are suffering from dementia and joining as a replacement case. In Worldwide, 50 million peoples are suffering from dementia.

Dementia affects the people in physiological, psychological, and group action. Dementia affects everyone in several way, based upon their personality changes and other behavioural changes dementia are often identified.

In the early stage of dementia, people gradually lose their character and starting some changes within the behaviour. within the middle stage dementia somewhat seen clearly by several the symptoms. The last stage is that the severe stage, it can't be cured.
People with dementia are frequently loses their basic rights and difficult to steer the traditional life. The families of affected people also suffer tons to survive. They face many problems within the society in physical, mental, and social pressure.

No impairment
Very mild cognitive decline
Moderate cognitive decline
Mild cognitive decline

Track 3: Molecular and Biology of Dementia

Molecular genetics (MG) may be a science concerned with the structure and performance of genes at the molecular level and includes the technique of gene-splicing, which may be defined because the direct manipulation of an organism's genome. the utilization of genetics in selection programmes rests on the power to work out the genotype of people for causal mutations or indirect markers using DNA analysis. However, a parent may pass certain genes that increase the danger of developing vascular dementia. the type of genes that increase the danger of vascular dementia are often an equivalent one that increase the danger of high vital sign, diabetes, heart condition and stroke.

Chronic illnesses that change or impair nerve cells and synapses concerned in cognition are the biological origin of dementia. At the present there are not any effective therapies to stop up or reverse the inherent disease process for the foremost common neurodegenerative diseases of elderly that cause dementia.

Track 4: Cognitive therapies of Dementia

Cognitive therapy may be a well-determined involvement for curing elderly concerned by dementia. especially, reality coordination and skills training seem to be useful interventions for reversing cognitive impairment among elderly, although findings are inconclusive.

Cognitive therapies are a valuable set of instruments used in many evidence-based psychotherapies. These methods are intended to help patients identify, challenge, and modify maladaptive thoughts, beliefs and images.

Cognitive Processing Therapy (CPT)
Cognitive Therapy (CT)
Dialectical Behavior Therapy (DBT)
Rational Emotive Behavior Therapy (REBT)
Self-Instructional Training.
Stress Inoculation Training, etc.

Track 5: Types of Dementia

Dementia may be a nerve related problem; it causes serious injuries and nerve related problems in brain. This condition is broadly categorized into various types; they are Alzheimer’s diseases, Lewy body dementia, front temporal dementia, Wernicke Korsakoff syndrome like that the primary syndrome is present. Alzheimer is that the commonest sort of syndrome within the dementia.

Wernicke Korsakoff is that the severe phase of the dementia, and another sort of this disorder is encephalopathy. it's the deficiency of the B-complex vitamin thiamine. Parkinson diseases influence the movement of the individual, often including shivers.
Huntington is that the critical condition during which the nerve cells within the breakdown over time. It usually starts during a person of 30’s and 40’s. Physiotherapy and talk therapy Treatment to cure these disorders

Alzheimer’s diseases.
Lewy body dementia.
Frontotemporal dementia.
Wernicke Korsakoff.
Parkinson’s diseases.
Huntington’s diseases.
Creutzfeldt-Jakob diseases.

Track 6: Vascular Dementia and Lewy body Dementia

Vascular dementia may be a common term explaining the substance established reasoning, planning, judgement, memory, and other thought process caused by the brain from the damaged blood vessels. This disease is especially happened within the older people with the obesity and diabetes. it's mostly caused at the upper risk of stroke.

It mainly affects the guts health, the seven stages of vascular dementia are, amnesia, communication problem, concentration problem, beholding problem and judgement problem. Alzheimer drugs may help to regulate cognitive syndrome. Vascular dementia stops the blood flow within the brain.

Each person experiences different sort of dementia based upon their body conditions. on the average people with vascular dementia live for around five years after the symptoms begins Lewy body dementia, also mentioned to as dementia with Lewy bodies, is that the second more common sort of continuing dementia after Alzheimer's disease. Protein accumulates, called Lewy bodies, develop in nerve cells within the brain sections involved in thinking, memory, and movement (motor control).

Vascular cognitive impairment.
Neurovascular dysfunction.
Geriatrics care practice and awareness neuroscience.

Track 7: Parkinson and Huntington Dementia

Parkinson's Disease Dementia. paralysis agitans dementia may be a decline in thinking and reasoning that develops in many of us living with Parkinson's a minimum of a year after diagnosis. Anxiety may be a common non-motor symptom of PD, and unfortunately, stress and anxiety can worsen motor symptoms of PD.

Cognitive impairments from PD can consist of memory complications, slowed feeling, misunderstanding, and/or dementia. Shifts to cognition may appear as distractibility, inefficiency, lack of memory, or difficulty solving problems.
Huntington's disease is a hereditary genomic condition that causes dementia. It causes a slow, progressive decline during a person's progress, memory, thinking and spirit.

Huntington's disease (HD) is an genetic disease that causes nerve cells (called neurons) in parts of the brain to gradually break down and die. The disease, which gets worse over time, attacks control regions of the brain (those involved movement), also as other areas.

Track 8: Geriatrics and Semantic Dementia

Dementia may be a deterioration in memory and other mental skills. As many as 8% of grown person aged 60 and older endure from dementia. alongside problems with memory, language, and decision-making abilities, dementia can cause other symptoms. These include mood change, like gradually increased prickliness, depression, and unease.
Semantic dementia (SD) thinking a progressive cognitive and language discrepancy, primarily affecting comprehension of words and related semantic managing. 1. These patients miss the sense of words, generally nouns, but retain eloquence, phonemics, and word order.

In the lobe sort of FTD, the initial symptom is usually a decrease in language skills. In semantic dementia, the power to assign pointing to words is slowly lost. Reading, spelling, comprehension, and expression are generally altered.

Track 9: Dementia Nursing

Dementia nursing provides the look after the dementia patient and improve their quality of life by giving some guidance. and provides some guidelines for his or her caretaker. Dementia nurses improve the mental quality of the dementia patient. Dementia nurse’s lookout of the conditions like, risk for trauma, chronic confusion, self-care deficit, risk for falls.

The nursing intervention for the dementia patient, orient client, encourage care givers about re-orientation, enforce with regeneration, explain simply, discourage suspiciousness of others, avoid cultivation of false ideas, Observe client closely. The nursing managing of a client with dementia include,

Nursing assessment.
Nursing diagnosis.
Nursing care planning and goals.
Nursing interventions.

Track 10: Neurology and Neurosurgery

Neurology is that the branch of drugs that deals with the study of systema nervosum within the brain. If any problem within the axon and therefore the outermost coverings it results in the loss of knowledge or loss of impulse to other areas. This results in the loss of memory functions like dementia and Alzheimer. Neurology accompanied with the central systema nervosum and peripheral systema nervosum. Peripheral systema nervosum contains all nerves outside of the systema nervosum .

Neurosurgery helps to cure the nerve related problem and retain patient to the traditional state. Neurosurgeons are broadly classified into three types: they're paediatric neurosurgeon, functional neurosurgeon, and oncology neurosurgeon. Paediatric neurosurgeons are wont to treat the facial bones within the skull, tumours, and congenital spine defects. Functional neurosurgeons are wont to manage the conditions like epilepsy, movement disorder and palsy. Oncology neurosurgeons are wont to manage the brain and spine tumours.

Neuro genetics
Neuropharmacology
Neuro immunology
Neuro paediatric
Neuro psychiatry
Neurological nursing
Neuro imaging
Neuro radiology
Paediatric neurosurgeon
Functional neurosurgeon
Oncology neurosurgeon

Track 11: Neuroimaging and Neurological Disorders

The most consistent findings in MRI studies of patients with AD are atrophy within the medial lobe (hippocampus, amygdala, entorhinal cortex and Para hippocampal gyrus), ventricular enlargement and smaller total brain volume. Doctors frequently request a CT or MRI scan of the brain once they are examining a patient with suspected dementia.

Neurological disorder is that the any disorder within the systema nervosum and causes problems within the brain and therefore the medulla spinalis . It changes the biochemical actions of the brain cells and results in variation within the structure.

Amyotrophic lateral sclerosis is that the progressive neurodegenerative disease that causes defect within the brain cells and therefore the medulla spinalis . The amyotrophic is comes from Greek language a way No, Myo means Muscle and Trophic means Nourishment, amyotrophic means No Muscle Nourishment.

Aneurysm refers to weakening of an artery valve results in the bulging of valves or distension that further creates the rupturing of artery valves results in the life-threatening conditions. In some cases, it doesn’t show any symptoms and it's going to not cause any dangerous, it suppressed.

Motor neuron diseases.
Prion diseases
Schizophrenia
Autism child.
ADD and ADHD.
Insomnia.

Track 12: Neuropharmacology and Neurodegenerative Diseases

Neuropharmacology is employed to review the characteristics of drug interaction with the cells present within the brain. The drug interaction with the cell within the two forms, Behavioural and Molecular. Behavioural neuropharmacology is employed to review the drug function within the brain and find how it changes the human behaviour.
Molecular pharmacology involves the study of neurons within the brain and finds the neurochemical interaction between each neuron.

Neurodegenerative disease is that the progressive degeneration of the central systema nervosum and peripheral systema nervosum . This gradual deterioration ends the function and structure of the brain. The widespread of neurodegenerative diseases are Alzheimer’s diseases, Parkinson’s diseases. Neurodegenerative diseases are untreatable conditions that end in gradual degeneration of nerve cells. Spinal muscular atrophy may be a sort of neurodegenerative diseases. Multiple sclerosis is that the disease during which the system eats the outer most covering of the nerve cells. during this case the treatment can prolong the life, it can't be cured. The symptoms of MS are vision loss, fatigue, pain, and impaired coordination.

Behavioural neuropharmacology
Molecular pharmacology
Amyotrophic lateral sclerosis
Aneurysm
Multiple sclerosis
Spinal cord injury.
Spinal muscular atrophy

Track 13: Pediatric Neurology

A child neurologist, or paediatric neurologist, may be a doctor who treats children who have problems with their systema nervosum . Problems within the systema nervosum can start within the brain, spine, nerves, or muscles. These can cause problems like seizures, headaches, or developmental delays.

A pediatric neurologist will see a good sort of patients. They treat more common neurological conditions like migraines, epilepsy, or spastic paralysis also as complex or rare conditions like traumatic brain injury, metabolic disorders, and degenerative neurological conditions.

Neonatal neurology
Pediatric neuromuscular diseases
Epilepsy
Autism

Track 14: Early and Younger onset of Dementia & Alzheimer

Alzheimer disease occurs in someone under age 65, it's referred to as early-onset (or younger-onset) Alzheimer disease. a small number of individuals with Alzheimer disease have the early-onset form.

The younger an individual is, the more likely genetics (familial history) are the explanation for early-onset dementia. Alzheimer's disease , vascular disease, FTD, and Dementia with Lewy bodies are more common causes of dementia in younger people.

Dementia may be a common term for a deterioration in capability severe enough to interfere with lifestyle . Alzheimer's is that the commonest explanation for dementia. Alzheimer's may be a specific disease.

Track 15: Amyloid Protein in Dementia

Amyloid protein creates the plaque or neurofibrillary tangle like formation. Neurofibrillary tangles are unsolvable warped fibres formed in between the brain cells. This causes the deprivation of the neurons and shows the symptoms of the Alzheimer’s diseases. Alzheimer diseases are caused thanks to the build-up of plaques in between the nerve cells within the brain. within the healthy brain, the protein molecules are break down and getting eliminated. The molecule is abnormal within the Alzheimer diseases causes collapse within the brain cells. The treatments for the amyloid protein are,

Amyloid plaques and neurofibrillary tangles
Cerebral Amyloid Angioplasty
Cerebrovascular Pathology
Cellular Signalling and cellular to cell transmission

Track 16: Bioinformatics Approach for Dementia and Alzheimer

Bioinformatics tools aid within the comparison of genetic and genomic data and more generally within the understanding of evolutionary aspects of biology . At a more consolidative level, it helps analyse and collection the biological pathways and networks that are a crucial a part of systems biology.

A key approach in Systems Bioinformatics is that the construction of multiple networks representing each level of the omics spectrum and their integration during a layered network that exchanges information within and between layers. Different disease modules are shown to act in synergy.

Thus, as revealed above, the common core aims of bioinformatics are to manage, evaluate, and understand the genome-derived molecular sequence data and its organizational principles in broad scales/spectra of comparative, simulative, and evolutionary/phylogenetics perspectives.

Track 17: Drug Development in Dementia

Dementia has only little treatment to regulate and cure the patient and much of treatment gone failure. Drug development for the dementia is that the tedious one. the primary drug was approved within the year 2003 and there's no other approval for the dementia drug development. So, the drug development for the dementia goes to be complex.

New research on dementia goes on using the amyloid, tau, and neurodegeneration condition within the national institute of aging. This framework produces the more stages of dementia. The drug discovery mainly specialises in the repurposing of the drugs, which suggests the drug is already used for several other conditions and this medicine is again used for the dementia with some modification therein chemicals. The drugs developed for dementia are

Gantenerumab
Solanezumab

Track 18: Animal Model and Translational Medicines

Animal models are the large trust for the researchers to seek out the drugs and ask that within the animals like testing mouse. within the animal model only support the Alzheimer diseases and closely connect the front temporal diseases. So mostly do the research within the Alzheimer diseases. Patients with Alzheimer’s illness can show the amyopathic and tauopathy.

Even though the anatomy of mouse is different than the human, the participant value is added. This has diode several corporations to concentrate on antibodies that block neurodegeneration in these mouse models.

Animal models of human psychological feature aging
Development of latest animal models
Genetic science of translational models
Protein-protein interactions

Track 19: Novel Therapeutics Targets and Mechanism for Treatment

The people endured by dementia losses their past activities and forgot the past enjoyment. Problem with amnesia can make nation harder to steer their lifestyle . Cognitive rehabilitation may be a sort of therapy which is employed to recover the dementia patient.
Physical therapy and rehabilitation services have many benefits to enhance the standard of life from the dementia and Alzheimer. This service is useful to alleviate the patient from the disease and improve the standard of life. The physiotherapist treatment includes the exercise. several the kinds of rehabilitation therapy include,

Occupational therapy.
Speech therapy.
Physical therapy.

Track 20: Causes, Symptoms of Alzheimer and Dementia

Dementia is identified by using some symptoms like problem with short memory, anxiety, depression, hearing disorder and headache. The STM loss is impact thanks to the concussion and trauma to the top . Medical conditions like seizures, epilepsy, heart bypass surgery and depression also can impact STM .

The disorder can cause a rise in pulse , shakiness, palpitations, pain, and high risk within the vital sign . People with anxiety disorders have hormone changes and defect within the chemical messenger areas. Anxiety attacks usually last in 10 minutes but it even may prolong for half-hour . During anxiety, the person loses their control at the short period of your time. In Alzheimer, Depression can affect an individual psychologically and it's the potential to vary the physical structures of the brain.

If anyone have problem associated with disorder within the family, it also exhibits within the next generation and causes dementia. And during this case, it causes the deterministic dementia.

Problem with short term memory
Anxiety problem
Depression leads to some effects Hearing impairment

Track 21: Prevention Measures

The foremost thanks to prevent the dementia is to take care of the traditional body function and interact with the opposite people and do some activity. the opposite main thanks to prevent dementia is eat healthy food. Eating of healthy food reduces the danger of dementia, avoid consuming of the fat rich content, rather than that only use the fibrous food. it'll increase the likelihood of person living without dementia.
Exercise helps to extend the blood and oxygen flow within the brain and helps to take care of the traditional psychological state of the person. Diet also helps to extend the stable psychological state .Instead of that use many whole grains, vegetables, and fruits. the amount of case studies shows that the strong reference to the social network reduces the danger of dementia and relieve the mental stress. thanks to this social interaction, it strengthens the connection between the nerve cells within the brain.

Physical exercise and diet
Social connection and intellectual activity
Eat healthy food

Track 22: Care Practice and Awareness

In the dementia care practice and awareness session, the caretaker should consider the physical conditions and therefore the food. it's the most thing that each caretaker should follow to recover the dementia patient.

The first look after the patient is to offer the healthy food and maintain the diet, consume great deal of fluid items and fibrous fruits rather than the fat content. The second care is to attach the dementia patient with the social network and check out to vary their psychological state .

Caretaker should continuously monitor the dementia patient and lookout of their food schedule. Caretaker not only follows the fitness and follows the mental condition of the patient. The steps should follow by the care takers includes,

Dementia Nursing
Psycho-Social Interventions
Cognitive Training
Dementia Management
Dementia Care Advances using Cloud Technology
Assistive Health Care

Track 23: Clinical Trials and Case Report

The goal of research on the dementia is to develop the drugs to recover them from the matter . it's occurred altogether over the planet . The clinical trials are done to see whether this method is safe or unsafe for the patient. Without the clinical research and caretaker there's no treatment for the dementia.

Medicines called cholinesterase inhibitors are advised for Normal to moderate dementia diseases. These drugs may help to cure the matter or suppress the matter . there's no standard treatment for dementia, but several the measures to take care of the psychological state of the patient.

Aducanumab may be a antibody an upscale drug to cure the dementia diseases. Function behind this method is that molecule binds with the drug to cure them. it's given through the intravenous vein once during a month. The antibodies used here is

Aducanumab
cholinesterase inhibitors

Track 24: Current Research in Therapeutic Targets

The professional opinion on therapeutic target is increased by 4.721 and it's 0.5 increased within the year of 2021. Studies have shown that amyloid-β (Aβ) protein deposition is an early event which will be within the development of Alzheimer’s, but the mechanisms that link Aβ to neurodegeneration are poorly understood, so require more research.

The report also states that clinically relevant symptoms tend to seem at an equivalent time as tau pathology is correlated with necrobiosis , meaning that prevention of the disease is difficult to review .

Furthermore, some parts of the brain like the hippocampus and amygdala seem to point out a selective weakness to plaque accumulation and tau-associated neurodegeneration, while others just like the cerebellum are initially spared. The list of improvements for dementia research includes:

Encouraging early drug discovery to identify targets
Investigating the effects of genetic risk factors on disease
Improving understanding of brain nerve cells are more resilient than others
Ensuring the right selection for clinical trials
Improving ways to measure the efficacy of drugs
Finding ways to begin clinical trials decades earlier than is currently conducted.

Market Analysis

The world Alzheimer’s therapeutics market was estimated at USD 4.0 billion in 2015 due to the increasing prevalence and predominance rates of this disease and growing geriatric population base. In 2015, it had been projected that 47 million people were being with Alzheimer’s Disease (AD) across the world. It mostly occurs within the older people that are 65 years and above. Furthermore, increasing awareness level regarding its symptoms, like partial dementia, is projected to spice up the demand.

The development of latest and advanced technologies is expected to contribute to the development of the general market. as an example, the event of latest cloud-based cognitive assessment systems is predicted to propel the growth. These systems help in identification of effects of medicine in patients. Hence, with the support of this technique, pharmaceutical companies can evaluate the ability and wellbeing of pipeline drugs for the treatment of this disease.

The increasing government funding for the Alzheimer’s care, regime, and research interests is valued to fuel the extension of this industry. Various organizations involved during this activity include the National Institute of Health (NIH), Alzheimer’s Association, and therefore the Florida Department of Health.

Recently, an alternative proposal referred to as Alzheimer’s Combination Therapy Opportunities was introduced together of Alzheimer’s Drug Discovery Foundation, Alzheimer’s Association, and Alzheimer’s Society UK. This proposal is anticipated to supply this market with growth opportunities. This proposal includes a mixture of repositioned or repurposed drugs that have the potential to hamper the progression of AD.

13^th International Conference on
Dementia and Alzheimers Disease

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Theme: Delving into the Advancements of Dementia and Alzheimers care