Amyloid Protein in Dementia
Amyloid beta (Aβ) protein plays a central role in the pathogenesis of dementia, particularly Alzheimer's disease. Aβ is a naturally occurring protein fragment derived from the larger amyloid precursor protein (APP). In healthy individuals, Aβ is cleared from the brain by mechanisms that include enzymatic degradation and transport across the blood-brain barrier. However, in individuals with dementia, Aβ accumulates in the brain, forming insoluble plaques that disrupt neuronal communication and contribute to cognitive decline.
Alzheimer's 2024 conference will feature a scientific session dedicated to amyloid beta protein in dementia, exploring the latest research on its role in disease development, potential therapeutic targets, and novel biomarkers for early diagnosis. Experts will discuss the mechanisms underlying Aβ accumulation and its impact on brain function. They will also present findings from clinical trials investigating anti-amyloid therapies and their potential to modify disease progression.