Scientific Program

Day 1 :

Keynote Forum

Hashim Missawi

Maria's Sudanese Charitable Association for Care of Alzheimer's Disease Patients, Sudan

Keynote: Non-pathological brain ageing vs dementia

Time :

Biography:

Hashim Missawi is currently working as a Consultant Pathologist and Head of Pathology Department at MMC Hospital, Ministry of Health Madinah Munawara, KSA. He is also a Member of Maria's Sudanese Charitable Association for Care of Alzheimer's Disease patients. He has completed his MBBS degree in 1982.

Abstract:

A leading character in life processes is their irreversibility, the fact that they are tied to the passage of time. The most common causes of death and suffering, even in most underdeveloped nations are age-related diseases. These diseases share fundamental and often have less appreciated pathology at the cellular and genetic levels. Ageing is a mandatory degenerative process that includes CNS (Central Nervous System) as well as other systems. Death is an unavoidable sequel that cannot be separated from the differentiation of cells, tissues and organs. Age-associated memory impairment is a part of ageing syndrome which includes changes that are deleterious, progressive, universal and thus far irreversible. Diseases of old age (diseases which increase in frequency with age, such as arthritis, osteoporosis, heart disease, Alzheimer's Disease, etc.) are often distinguished from aging per second. Senescent cells accumulate with age and contribute to age-related declines in brain function. At the same time cellular senescence prevents the unregulated growth and malignant transformation of proliferating cells as indicated by the decreasing incidence of brain tumors with advanced ageing. A sharp demarcation between normal brain ageing and Alzheimer's disease can be achieved by understanding the pathogenesis of the latter. A good example is the evaluation of amyloid deposition which can provide a solid base for specific and efficient treatment for Alzheimer's disease but not for
ageing.

Keynote Forum

Eduardo Garcia-Toledano

World Rare Disorders Foundation & Childhood Cancer Foundation, Spain

Keynote: Management of physical health conditions in adults with severe mental disorders

Time : 10:40 to 11:20

Biography:

Eduardo Garcia-Toledano is currently working as a Vice President and General Counsel of Global Health, Madrid, Spain. He is heading up the group responsible for the foundation's external liaison with all stakeholders working to support the availability of treatments for childhood cancer and rare diseases on behalf of the company. He has worked on programs for the Spanish Government Ministry of Health, social services and equality. His career has been focused on patient care and case management for patients with chronic and rare diseases, working with laboratories and orphan drugs helping people who need help and are suffering from rare and chronic diseases.

Abstract:

The global burden of disease due to mental disorders continues to rise, especially in Low- and Middle-Income Countries (LMIC). In addition to cause a large proportion of morbidity, mental disorders, especially Severe Mental Disorders (SMD) are linked with poorer health outcomes and increased mortality. SMD are defined as a group of conditions that include moderate to severe depression, bipolar disorder and schizophrenia and other psychotic disorders. People with SMD have two to three times higher average mortality compared to the general population, which translates to a 10-20-year reduction in life expectancy. The WHO Comprehensive Mental Health Action Plan (2013-2020) outlines a vision where people living with mental disorders can exercise the full range of human rights and to access high quality, culturally-appropriate health and social care in a timely way to promote recovery. In service of this vision and as part of WHO’s mental health Gap Action Program (mhGAP), these guidelines on the management of physical health conditions in adults with severe mental disorders will provide up-to-date, evidence-based recommendations to support the scale-up of care for physical health conditions and their risk factors affecting people living with SMD globally. Existing WHO guidelines for the general population are relevant to the physical health conditions that increase the morbidity and mortality for people with SMD, for example, the Package of Essential Non-communicable (PEN) disease interventions for primary health care in low-resource.

  • Dementia | Alzheimer and Parkinson | Epilepsy | Multiple Sclerosis| Migraine | Prion Disease | Motor Neurone Diseases | Huntingtons Disease | Cognitive Impairment |Stroke
Location: Madrid
Speaker
Biography:

Javier Obis is an Ophthalmologist, has expertise in ophthalmological alterations related to Parkinson’s disease. He has published several articles in PubMed about retinal and choroid alterations measured with OCT in neurological diseases, especially in PD. He has researches on visual alterations related with PD and other neurological diseases. He is currently working on his doctoral thesis, which studies the retinal and choroid thickness alterations that appear in patients with PD and also the visual alterations that these patients suffer.

Abstract:

Parkinson’s Disease (PD) is a neurodegenerative process that causes a selective loss of dopaminergic neurons, mainly in the basal ganglia. It also affects the intra retinal dopaminergic circuitry. Optical Coherence Tomography (OCT) is a non-invasive imaging technique which is used in ophthalmology to evaluate the layers of the retina and choroid (the vascular layer that nourishes the retinal
cells). Since 2004, several studies have proved changes on various retinal layers in PD using OCT; however, there are discrepancies among their results. Some of them have correlated retinal thickness with the severity or duration of the disease, demonstrating that OCT measurements may be an innocuous and easy biomarker for PD progression. Other studies have demonstrated visual dysfunctions since early phases of the disease. Lastly, the most recent studies that use Swept Source OCT technology, have found choroidal thickness increase in PD patients.

Hamid Hassbrabu

Maria's Sudanese Charitable Association for Care of Alzheimer's Disease Patients, Sudan

Title: Alzheimer vs legal liability
Speaker
Biography:

Hamid Hassbrabu Alsubaei has completed his Master’s in Criminal Psychology from Khartoum University. He is currently pursuing his PhD from Khartoum University, Sudan in Criminal Psychology

Abstract:

Today, number of people with Alzheimer is higher and increasing faster than ever before. This phenomenon as it creates social and health problems, in the meantime makes unavoidable legal dilemmas that are to be discussed and heighted, researched and solved. This paper aims at shedding a light on whether those individuals whose symptoms, suffer and diagnosed as Alzheimer are to be involved in the legal system or not? The paper will examine these issues such as Those Individuals whose symptoms, suffer and diagnosed as Alzheimer, what is status of their fi tness to stand trial and at which stage of Alzheimer’s disease patient can be legally responsible for their civil and criminal acts.

Hashim Missawi

Maria's Sudanese Charitable Association for Care of Alzheimer's Disease Patients, Sudan

Title: Clinicopathological correlation and laboratory investigations in dementia
Speaker
Biography:

Hashim Missawi is currently working as a Consultant Pathologist and Head of Pathology Department, MMC Hospital, Ministry of Health Madinah Munawara, KSA. He is also a Member of Maria's Sudanese Charitable Association for Care of Alzheimer's Disease Patients. He has completed his MBBS degree and his objective is to further widen and develop experience in pediatric and geriatric pathology and laboratory quality control.

Abstract:

Dementias including Alzheimer's disease are the most common terminal illnesses amongst ageing populations and their prevalence continues to increase along with increased human life expectancy. Based on clinical criteria alone, the diagnosis cannot be made until the disease is in a relatively far advanced stage. Neuropathology accumulates gradually and it has been shown that neuro pathological features, eventually leading to the clinical syndrome of dementia, may be present as early as 20 years before the first symptoms become overt. Relevant laboratory techniques are required to classify the complex dynamic neuro-anatomical changes that occur over time in health and disease. With the advent of potential therapies for the treatment of degenerative dementias, clinical pathology strategies need to enable early diagnosis and facilitate monitoring of disease progression in treatment trials.

Speaker
Biography:

Javier Obis is an Ophthalmologist, has expertise in ophthalmological alterations related to Parkinson’s disease. He has published several articles in PubMed about
retinal and choroid alterations measured with OCT in neurological diseases, especially in PD. He has researches on visual alterations related with PD and other neurological diseases. He is currently working on his doctoral thesis, which studies the retinal and choroid thickness alterations that appear in patients with PD and also the visual alterations that these patients suffer.

Abstract:

Parkinson’s Disease (PD) is a neurodegenerative process that causes a selective loss of dopaminergic neurons, affecting the basal ganglia and also the intra retinal dopaminergic circuitry. Optical Coherence Tomography (OCT) is a non-invasive
imaging technique used in ophthalmology to evaluate the layers of the retina. The study aims to evaluate changes in the macular thickness and in the Retinal Nerve Fiber Layer (RNFL) after a 4 years follow up in patients with PD.

Speaker
Biography:

Abrar Nadir Aljaily is currently a MBBS student in Nile University, Sudan and she is also a Member of Maria Charitable Association for Alzheimer’s patients.

Abstract:

Mrs. Maria 64 -year-old Sudanese female, a teacher her family history includes her father with dementia who is in his 70s. on 2005 she had chronic low back pain extending to the lower extremities she had also neck pain which diagnosed as malignant lymphoma with Central Nervous System (CNS) involvement she received chemotherapy biological engineering drug Rituximab injection and radiotherapy during the year of 2005 and 2006. She was followed up by oncology since then. Mrs. Maria started to have gradual memory impairment and deterioration of her cognitive function during her chemotherapy on 2006 her recent memory was mainly affected more than the remote one.

Speaker
Biography:

Eithar Nader Aljaily has completed her Bachelor of Architecture from Future University, Sudan. She is also a Member of MARIA Charitable Association and
Architecture Association at Future University.

Abstract:

Project definition: Alzheimer’s respite center provides flexible short-term care for people suffering from Alzheimer’s and long term for homeless people suffering from Alzheimer disease as well as offering a means of support for the affected families.
Aim: Lack of attention to provide the appropriate environment for Alzheimer’s in Sudan, lack of awareness of Alzheimer and how to deal with it.

Day 2 :

  • Huntingtons Disease |Spinocerebellar Ataxia| Spinal Muscular Atrophy | Demyelinating Diseases | Headache
Location: Madrid

Session Introduction

Sana AlBustan

Kuwait University, Kuwait

Title: Parkinson Disease: A study of public awareness in Kuwait
Speaker
Biography:

Sana AlBustan is working in Dept. of Communication Sciences and Disorders in College of Life Sciences under Kuwait University. 

Abstract:

Purpose: The intended study would shed a light on Parkinson Disease (PD)in Kuwait. This study will represent the levels of awareness and knowledge among general people about PD that are currently not very well documented in Kuwait. Research Methodology: A questionnaire will be developed for this current study by the researcher that would consist of a structured item questionnaire that would compose of both open-ended and close-ended questions would be given to 50 males and 50 females after a committee of professionals in the field approve the questionnaire. Questions will be devolved to address various aspects of the definition PD, onset of PD, cause, treatment, and hereditariness Demographic data with participants demographic features such as age, gender, occupations, qualifications and educational level will also be considered and addressed in this research. SPSS analysis procedures will be used to examine and analyze the participants responses. Results: The study is still in its pre-implementation stage progress. The researcher anticipates her results will be consistent with other researchers’ findings. Important and new information that the present study might contribute: The primary goal of this study is to investigate the level of public awareness and knowledge of PD and facilitate the level of awareness and the services offered by governmental and private medical facilities in the Kuwait.

Speaker
Biography:

Ahed J Alkhatib is currently working as a researcher in Department of Forensic Science and Toxicology, Jordan University of Sciences and Technology, Jordon from 2011 to till date. He completed his PhD in Campbell University, medical technology, North Carolina, USA from 2008 to 2011.

Abstract:

Alzheimer’s disease is a disease associated with neurodegenerative nature. We look for this disease in depth and think that functional alterations in white matter precede the clinical onset of Alzheimer’s disease. As it were, it involves cerebrum maturing that happen by years (might be 5 years) before Alzheimer's infection had been created. This period is characterized by depression, which partly may be due to memory declining episodes. It was interestingly found that patients with diabetes are more likely to develop Alzheimer’s disease. We have found using experimental animal models that rats with diabetes exhibited functional abnormalities in white matter. In other words, we found two biomarkers with different expressions, the expression of inducible Nitric Oxide Synthase (iNOS) was highly expressed in white matter of diabetic rats compared with expression of iNOS in grey matter of the same group (p=0.000). On the other hand, the expression of heat shock protein 70 (Hsp70) exhibited different biological reactivity in which its expression was signifi cantly decreased in white matter compared with that in grey matter of the same group (p=0.000).

Speaker
Biography:

Radu Mutihac is Chair of Medical Physics Section, University of Bucharest, and works in Neuroscience, Signal Processing, Microelectronics, and Artificial Intelligence. 

Abstract:

Alzheimer’s disease is a disease associated with neurodegenerative nature. We look for this disease in depth and think that functional alterations in white matter precede the clinical onset of Alzheimer’s disease. As it were, it involves cerebrum maturing that happen by years (might be 5 years) before Alzheimer's infection had been created. This period is characterized by depression, which partly may be due to memory declining episodes. It was interestingly found that patients with diabetes are more likely to develop Alzheimer’s disease. We have found using experimental animal models that rats with diabetes exhibited functional abnormalities in white matter. 

Speaker
Biography:

Beenish Asrar have been awarded the Indigenous PhD grant for her home country; 6-month research fellowship abroad, a travel grants for phenotyping course, system genetics by EMBO, and a travel grant for course at University of Luxembourg by Radboud University, Nijmegen. She is a young, ambitious, scientist, just started my scientific career. 

Abstract:

Speaker
Biography:

Shaista S Kazmi BA is working at APNA GHAR LLC the first senior care agency to serve the needs of the Elderly Southeast Asian community. 

Abstract:

The most rapidly growing age demographic in the United States is elders from minority groups. This changing dynamic will call for attention to the needs, challenges and experiences of these groups. With the elderly minority population rising in the United States, the challenge will be how can health care professionals provide both institutional and non institutional services for elderly ethnic minorities. Although Alzheimer is vastly recognized throughout the world, elderly minorities are the last to be diagnosed with the disease. Cultural taboos and social stigma cause this group in particular not to seek help.

Dalamagka Maria

General hospital of Larissa, Greece

Title: Neuropathic pain
Speaker
Biography:

Dalamagka Maria, PhD (Pain medicine doctor, Aristotle University, Greece), consultant anesthetist (General Hospital of Larissa, Greece), teacher and trainer, acupuncturist,.

Abstract:

Background and purpose: Neuropathic pain (NP) is often refractory to pharmacologic and non-interventional treatment. Neuropathic pain can be distinguished from non-neuropathic pain by two factors. In neuropathic pain there is no transduction (conversion of a nociceptive stimulus into an electrical impulse). Finally, injury to major nerves is more likely than injury to non-nervous tissue to result in chronic pain. This review focuses on the clinical treatment of neuropathic pain as well aims to improve the care of adults with neuropathic pain. Methods: Clinical treatment of neuropathic pain depends on clinical evaluation, as treatment can be pharmacological or not; invasive treatment or other therapies. Results: Neuropathic pain because of its heterogeneity, there is often uncertainty regarding the nature and exact location of a lesion or health condition associated with neuropathic pain. Conclusions: Both peripheral and central nervous system mechanisms contribute to the persistence of most types of neuropathic pain. . Patients with conditions as diverse as diabetic polyneuropathy, human immunodeficiency virus (HIV) sensory neuropathy, poststroke syndromes, and multiple sclerosis frequently experience daily pain that greatly impairs their quality of life. Implications: Progress in basic science will lead to a greater understanding of the pathophysiologic mechanisms of neuropathic pain. 

  • Cerebral Palsy | Cognitive Impairment | Convulsion | Neurologist | Neurodegeneration | Neuropathy
Location: Madrid